MAPK8 XENOPUS

Name: Mitogen-activated protein kinase 8 - xenopus

Alternative names: JNK1,JNK-46, SAPK1, Prkm8

Taxonomy: [Xenopus laevis] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.

Protein Size: 426 aa

mRNA Size: 3227 bp

MW: 47928 Da

pI: 6.20

Activator MKKs: MAP2K4 (MKK4};MAP2K5 (MKK5); MAP2K7 (MKK7)

Activation site: TPY (pThr-183 and pTyr-185)

Protein sequence [FASTA]:

>mkr|XEL000008|MK8_XENOPUS|Mitogen-activated protein kinase 8 
MSRSKRDSNFSVFEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAFDAVLERHVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDLYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCILGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCTEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDDALQHPYINVWYDPLEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
LDWEERAKNGVIRGQPAPLGAAVTDGSQAHTSSSSGDASSMSTDPTLPSDTDSSLETSAG
TLGCCR

Cross references

RefSeq: Protein: NP_001080184.1. Nucleotide sequence: NM_001086715.1.
NCBI Gene: 379876 [ MAPK8 mitogen-activated protein kinase 8 ]
UniProtKB: Q8QHK8 [ MAPK8 ]