MAPK7 HUMAN

Name: Mitogen-activated protein kinase 7 - human

Alternative names: Erk5, BMK-1, Prkm7

Taxonomy: [Homo sapiens] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo.

Protein Size: 816 aa

mRNA Size: 3183 bp

MW: 88386 Da

pI: 5.6

Activator MKKs: MAP2K3 (MKK3); MAP2K6 (MKK6)

Activation site: TEY (pThr-219 and pTyr-221)

Protein sequence [FASTA]:

>mkr|HOS000007|MK7_HUMAN|Mitogen-activated protein kinase 7 
MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP

Cross references

RefSeq: Protein: NP_620602.2. Nucleotide sequence: NM_139033.2.
RefSeq: Protein: NP_620601.1. Nucleotide sequence: NM_139032.2.
RefSeq: Protein: NP_002740.2. Nucleotide sequence: NM_002749.3.
RefSeq: Protein: NP_620603.2. Nucleotide sequence: NM_139033.2.
NCBI Gene: 5598 [ MAPK7 mitogen-activated protein kinase 7 ]
UniProtKB: Q13164 [ MAPK7 ]
NextProt: NX_Q13164 [ Mitogen-activated protein kinase 7 ]
HPRD: 03952 [ MAPK7 ]
RCSB PDB: 4B99 [ MAPK7 ]