About project

The mission of The MAP Kinase Resource is to collect the information about MAP kinases, shear it with a scientific community, students and all other interested. We would also like to improve communications between medical and life science professionals who are interested in MAPkinases.

The MAP Kinase Resource Website was created in 1998. The inspiration at the time came from other specialized websites, such as websites on receptors, transcription factors, etc.

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MAP Kinase Journal

MAP Kinase Journal

“MAP Kinase” is the first journal to concentrate specifically on the Mitogen-activating protein kinase family of protein kinases. MAP kinases are serine/threonine protein kinases that respond to extracellular stimuli and regulate various cellular activities, such as apoptosis, gene expression, mitosis, differentiation and immune responses, to name just a few. The MAP kinase family consists of four major subfamilies of related proteins (Erk1/2, JNK, p38 and Erk5) that make up interconnected signal transduction cascades activated by external stimuli, such as growth factors, stress, cytokines and inflammation...

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MAPK Resource

MAPK Resource

MAP Kinase Resource website is a MAP kinase database, based on NCBI protein sequences. Here you can find the sequences of all MAP kinases in different species. This database will be constantly renewed and your input is especially welcome!

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Researchers

Researchers

Researchers – the database of scientists interested in MAP kinases. If your are looking for a potential collaborator, employer or a person who could answer your questions, share a plasmid or an antibody with you, this is the right place for you. Moreover, if you had published at least one paper in MAP kinase field, you are welcome to add yourself to the list!

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ERK1/2

ERK1/2

The ERKs (MAPK p42/p44) are the prototypic MAPKs and are activated by a variety of mitogenic stimuli as well as differentiation signals. MAPK activation largely requires Ras activation. In Drosophila, the ERK homologue is encoded by the Rolled locus (an activated allele) which has been placed downstream of Ras in the sevenless receptor kinase pathway.

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Protocols

Protocols

Protocols – need a help with an assay? Have a looke here, maybe you will find what you are looking for. The founder of MAP Kinase Resource is sharing his experience on stuff he knows to work!

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Nomenclature

Nomenclature

Probably the hardest thing in Cell Signaling research is the fact, that most of the molecules have many alternative names. It is sometimes hard to figure out, which kinase people are talking about if one doesn`t know the alternative names. You will find a list of all possible alternative names of mammalian MAP kinases.

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Plasmid donations

Plasmid donations

MAP Kinase Research invites all scientists to donate their MAP kinase constructs in any vectors. We are trying to create a database of MAP kinase constructs (wild type genes, mutants, tagged constructs etc.) for the use of all scientific community. All those, who are willing to send their constructs,

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Community

Community

If you are interested in MAP kinases, you are definitely not alone! The forum should help us come together and discuss any aspects of MAP kinase research. We can discuss protocols, papers, hypotheses and any other aspect of MAPKs. We can even share hobbies or jokes!

Anyone is welcome to join



Writing for MAPK resource
MAP kinase resource community
MAP Kinase Wiki
MAP Kinase Conference 2014

Latest MAP Kinase news

The Biochemistry, Biology and Pathology of MAP Kinases II, September 11-12, 2014, Vilnius, Lithuania

It`s our pleasure to invite you to the international event "The Biochemistry, Biology and Pathology of MAP Kinases II". The conference is organized by Enterprise Lithuania together with Swiss...

Next-Gen Kinase Inhibitors Conference - Cambridge Healthtech Institute, June 17 - 19, 2013

This established and well-recognized kinase conference addresses reoccurring questions about selectivity, safety, resistance and novelty. After many years of research and therapeutic developments of...

Control of the cell cycle progression by the MAPK Hog1

Eukaryotic cells coordinate various intracellular activities in response to environmental stresses, activating an adaptive program to maximize the probability of survival and proliferation. Cells...

Ultrasensitive MAPK/Erk activation in absence of protein synthesis in Xenopus oocytes

The mitogen-activated protein kinase (MAPK) cascade in Xenopus oocytes exhibits an all-or-none, ultrasensitive response, which is believed to result from a positive feed-back loop. Here we describe a...

Batsheva de Rothschild Seminar on Biochemistry, Biology and Pathology of MAP Kinases

This abstract book contains most of the abstracts presented to the Batsheva de Rothschild Seminar on Biochemistry, Biology and Pathology of MAP Kinases. An Aharon Katzir-Katchalski Meeting and an...


Project Sponsors & Friends


Swiss Institute of Bioinformatics Journalism differently - journalism about mass media

Lithuanian Biotechnology Association Enterprise Lithuania

PAGEPress Publications - scholarly open access journals International Society for Biocuration

brightstat.com

European Bioinformatics Institute

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